Supplementary materials – poolMC: Smart pooling of mRNA samples in microarray experiments

Here we describe at greater length the mathematical basis and practical implementation of the poolMC smart pooling strategy. Also included are complete versions of the figures used in the paper to analyze the performance of poolMC in a pooled microarray experiment. Pooling strategy Several pooling methods have been discussed in the literature [1, 2] (Note: The reference numbers pertain to those cited in this document not the main paper). The design shown in Figure 2 of the paper and used in the experiment was based on an expander graph construction used by Berinde et. al. [3], which is defined as follows. A (k,)-unbalanced expander is a bipartite simple graph G – (A, B, E) with left degree d such that for any